Preheat oven to 350°F (175°C). Spray a 9x13-inch baking pan with nonstick cooking spray and set aside.
Coarsely chop the Lay’s Wavy Original potato chips; measure 1 1/4 cups chopped chips for the batter and set aside 1/4 cup chopped chips for the top.
In a medium bowl, whisk together 2 1/8 cups all-purpose flour, 3/4 teaspoon sea salt, and 1/2 teaspoon baking soda. Set the dry mixture aside.
Melt 12 tablespoons butter, then let it cool to room temperature. (If the butter is already melted and cooled, proceed.)
In a large bowl (or the bowl of a stand mixer), combine the cooled melted butter with 1 cup packed light brown sugar and 1/2 cup granulated sugar until combined.
Add 2 large eggs (at room temperature) and 2 teaspoons vanilla extract to the butter-sugar mixture and mix until smooth.
Gradually add the dry ingredients to the wet ingredients and mix on low speed (or stir gently with a spatula) just until combined—do not overmix.
Fold in 1 1/4 cups semi-sweet chocolate chips and the 1 1/4 cups chopped potato chips until evenly distributed.
Pour the blondie batter into the prepared 9x13-inch pan and smooth the top with a spatula. Sprinkle the reserved 1/4 cup chopped potato chips evenly over the top, and lightly sprinkle with sea salt.
Bake for 28–30 minutes, or until the top is light golden brown and the edges begin to pull away from the pan.
Remove the pan from the oven and transfer to a wire rack. Cool completely to room temperature in the pan.
Once cooled, cut into squares and serve.